Resources for Identifying
Research Literature
In the following guide, you will find a selection of Evidence Based Practice Resources. If you have any questions, do not hesitate to contact a librarian at Bracken Health Sciences library.
Resources listed in this section provide some type of evidence based analysis, synthesis and/or summary of a particular topic, study or question that will aid in evidence based decision making.
Includes databases that are useful for identifying clinical trials.
Clinical practice guidelines gather, appraise and combine evidence. They attempt to address all the issues relevant to a clinical decision.
CMA Infobase: clinical practice guidelines
Guideline Advisory Committee (GAC)
National Guideline Clearinghouse
Toward Optimized Practice (TOP)
Four journal article series highlighting important concepts in evidence-based medicine are assembled: JAMA Series: "Users' Guide to the Medical Literature", BMJ Series: "How to Read a Paper", CMAJ Series: "Evidence-Based Medicine Teaching Tips", and JGIM Series: "Tips for Teachers of Evidence-Based Medicine".
(1) Guyatt GH, Haynes RB, Jaeschke RZ et al. Users' Guides to the Medical Literature: XXV. Evidence-based medicine: principles for applying the Users' Guides to patient care. Evidence-Based Medicine Working Group.[see comment]. JAMA 284(10):1290-6, 2000 September 13.
(2) Richardson WS, Wilson MC, Williams JW, Jr., Moyer VA, Naylor CD. Users' guides to the medical literature: XXIV. How to use an article on the clinical manifestations of disease. Evidence-Based Medicine Working Group. JAMA 284(7):869-75, 2000 August 16.
(3) Giacomini MK, Cook DJ. Users' guides to the medical literature: XXIII. Qualitative research in health care B. What are the results and how do they help me care for my patients? Evidence-Based Medicine Working Group. JAMA 284(4):478-82, 2000 July 26.
(4) Giacomini MK, Cook DJ. Users' guides to the medical literature: XXIII. Qualitative research in health care A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA 284(3):357-62, 2000 July.
(5) McGinn TG, Guyatt GH, Wyer PC, Naylor CD, Stiell IG, Richardson WS. Users' guides to the medical literature: XXII: how to use articles about clinical decision rules. Evidence-Based Medicine Working Group. JAMA 284(1):79-84, 2000 July 5.
(6) McAlister FA, Straus SE, Guyatt GH, Haynes RB. Users' guides to the medical literature: XX. Integrating research evidence with the care of the individual patient. Evidence-Based Medicine Working Group.[see comment]. JAMA 283(21):2829-36, 2000 June 7.
(7) Hunt DL, Jaeschke R, McKibbon KA. Users' guides to the medical literature: XXI. Using electronic health information resources in evidence-based practice. Evidence-Based Medicine Working Group. JAMA 283(14):1875-9, 2000 April 12.
(8) McAlister FA, Laupacis A, Wells GA, Sackett DL. Users' Guides to the Medical Literature: XIX. Applying clinical trial results B. Guidelines for determining whether a drug is exerting (more than) a class effect.[see comment]. JAMA 282(14):1371-7, 1999 October 13.
(9) Bucher HC, Guyatt GH, Cook DJ, Holbrook A, McAlister FA. Users' guides to the medical literature: XIX. Applying clinical trial results. A. How to use an article measuring the effect of an intervention on surrogate end points. Evidence-Based Medicine Working Group. JAMA 282(8):771-8, 1999 August 25.
(10) Randolph AG, Haynes RB, Wyatt JC, Cook DJ, Guyatt GH. Users' Guides to the Medical Literature: XVIII. How to use an article evaluating the clinical impact of a computer-based clinical decision support system. JAMA 282(1):67-74, 1999 July 7.
(11) Barratt A, Irwig L, Glasziou P et al. Users' guides to the medical literature: XVII. How to use guidelines and recommendations about screening. Evidence-Based Medicine Working Group. JAMA 281(21):2029-34, 1999 June 2.
(12) Guyatt GH, Sinclair J, Cook DJ, Glasziou P. Users' guides to the medical literature: XVI. How to use a treatment recommendation. Evidence-Based Medicine Working Group and the Cochrane Applicability Methods Working Group. JAMA 281(19):1836-43, 1999 May.
(13) Richardson WS, Wilson MC, Guyatt GH, Cook DJ, Nishikawa J. Users' guides to the medical literature: XV. How to use an article about disease probability for differential diagnosis. Evidence-Based Medicine Working Group. JAMA 281(13):1214-9, 1999 April 7.
(14) Dans AL, Dans LF, Guyatt GH, Richardson S. Users' guides to the medical literature: XIV. How to decide on the applicability of clinical trial results to your patient. Evidence-Based Medicine Working Group.[see comment]. JAMA 279(7):545-9, 1998 February 18.
(15) O'Brien BJ, Heyland D, Richardson WS, Levine M, Drummond MF. Users' guides to the medical literature. XIII. How to use an article on economic analysis of clinical practice. B. What are the results and will they help me in caring for my patients? Evidence-Based Medicine Working Group.[erratum appears in JAMA 1997 Oct 1;278(13):1064]. JAMA 277(22):1802-6, 1997 June 11.
(16) Drummond MF, Richardson WS, O'Brien BJ, Levine M, Heyland D. Users' guides to the medical literature. XIII. How to use an article on economic analysis of clinical practice. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA 277(19):1552-7, 1997 May 21.
(17) Guyatt GH, Naylor CD, Juniper E, Heyland DK, Jaeschke R, Cook DJ. Users' guides to the medical literature. XII. How to use articles about health-related quality of life. Evidence-Based Medicine Working Group. JAMA 277(15):1232-7, 1997 April 16.
(18) Naylor CD, Guyatt GH. Users' guides to the medical literature. XI. How to use an article about a clinical utilization review. Evidence-Based Medicine Working Group. JAMA 275(18):1435-9, 1996 May 8.
(19) Naylor CD, Guyatt GH. Users' guides to the medical literature. X. How to use an article reporting variations in the outcomes of health services. The Evidence-Based Medicine Working Group. JAMA 275(7):554-8, 1996 February 21.
(20) Guyatt GH, Sackett DL, Sinclair JC, Hayward R, Cook DJ, Cook RJ. Users' guides to the medical literature. IX. A method for grading health care recommendations. Evidence-Based Medicine Working Group.[erratum appears in JAMA 1996 Apr 24;275(16):1232]. JAMA 274(22):1800-4, 1995 December 13.
(21) Wilson MC, Hayward RS, Tunis SR, Bass EB, Guyatt G. Users' guides to the Medical Literature. VIII. How to use clinical practice guidelines. B. what are the recommendations and will they help you in caring for your patients? The Evidence-Based Medicine Working Group. JAMA 274(20):1630-2, 1995 November 22;-29.
(22) Hayward RS, Wilson MC, Tunis SR, Bass EB, Guyatt G. Users' guides to the medical literature. VIII. How to use clinical practice guidelines. A. Are the recommendations valid? The Evidence-Based Medicine Working Group. JAMA 274(7):570-4, 1995 August 16.
(23) Richardson WS, Detsky AS. Users' guides to the medical literature. VII. How to use a clinical decision analysis. B. What are the results and will they help me in caring for my patients? Evidence Based Medicine Working Group. JAMA 273(20):1610-3 1995 May 24;-31.
(24) Richardson WS, Detsky AS. Users' guides to the medical literature. VII. How to use a clinical decision analysis. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA 273(16):1292-5 1995 April 26.
(25) Oxman AD, Cook DJ, Guyatt GH. Users' guides to the medical literature. VI. How to use an overview. Evidence-Based Medicine Working Group.[see comment]. JAMA 272(17):1367-71, 1994 November 2.
(26) Laupacis A, Wells G, Richardson WS, Tugwell P. Users' guides to the medical literature. V. How to use an article about prognosis. Evidence-Based Medicine Working Group. JAMA 272(3):234-7, 1994 July.
(27) Levine M, Walter S, Lee H, Haines T, Holbrook A, Moyer V. Users' guides to the medical literature. IV. How to use an article about harm. Evidence-Based Medicine Working Group. AMA 271(20):1615-9, 1994 May 25.
(28) Jaeschke R, Guyatt GH, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA 271(9):703-7, 1994 March 2.
(29) Jaeschke R, Guyatt G, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA 271(5):389-91, 1994 February 2.
(30) Guyatt GH, Sackett DL, Cook DJ. Users' guides to the medical literature. II. How to use an article about therapy or prevention. B. What were the results and will they help me in caring for my patients? Evidence-Based Medicine Working Group. JAMA 271(1):59-63, 1994 January 5.
(31) Guyatt GH, Sackett DL, Cook DJ. Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA 270(21):2598-601, 1993 December 1.
(32) Oxman AD, Sackett DL, Guyatt GH. Users' guides to the medical literature. I. How to get started. The Evidence-Based Medicine Working Group. JAMA 270(17):2093-5, 1993 November 3.
(1) Greenhalgh T. How to read a paper. Papers that report diagnostic or screening tests.[see comment][erratum appears in BMJ 1997 Oct 11;315(7113):942]. BMJ 315(7107):540-3, 1997 August 30.
(2) Greenhalgh T, Taylor R. Papers that go beyond numbers (qualitative research)[see comment]. BMJ 315(7110):740-3, 1997 September.
(3) Greenhalgh T. Papers that summarise other papers (systematic reviews and meta-analyses). BMJ 315(7109):672-5, 1997 September 13.
(4) Greenhalgh T. How to read a paper. Papers that tell you what things cost (economic analyses). BMJ 315(7108):596-9, 1997 September 6.
(5) Greenhalgh T. How to read a paper. Papers that report drug trials. BMJ 315(7106):480-3, 1997 August 23.
(6) Greenhalgh T. How to read a paper. Statistics for the non-statistician. II: "Significant" relations and their pitfalls. BMJ 315(7105):422-5, 1997 August 16.
(7) Greenhalgh T. Assessing the methodological quality of published papers.[see comment]. BMJ 315(7103):305-8, 1997 August 2.
(8) Greenhalgh T. How to read a paper. Statistics for the non-statistician. I: Different types of data need different statistical tests.[erratum appears in BMJ 1997 Sep 13;315(7109):675]. BMJ 315(7104):364-6, 1997 August 9.
(9) Greenhalgh T. How to read a paper. Getting your bearings (deciding what the paper is about).[see comment]. BMJ 315(7102):243-6, 1997 July 26.
(10) Greenhalgh T. How to read a paper. The Medline database.[see comment]. BMJ 315(7101):180-3, 1997 July.
(1) Montori VM, Wyer P, Newman TB, Keitz S, Guyatt G, Evidence-Based Medicine Teaching Tips Working Group. Tips for learners of evidence-based medicine: 5. The effect of spectrum of disease on the performance of diagnostic tests. CMAJ: Canadian Medical Association Journal 173(4):385-90, 2005 August 16.
(2) Hatala R, Keitz S, Wyer P, Guyatt G, Evidence-Based Medicine Teaching Tips Working Group. Tips for learners of evidence-based medicine: 4. Assessing heterogeneity of primary studies in systematic reviews and whether to combine their results. CMAJ: Canadian Medical Association Journal 172(5):661-5, 2005 March 1.
(3) McGinn T, Wyer PC, Newman TB et al. Tips for learners of evidence-based medicine: 3. Measures of observer variability (kappa statistic).[see comment][erratum appears in CMAJ. 2005 Jul 5;173(1):18]. CMAJ: Canadian Medical Association Journal 171(11):1369-73, 2004 November 23.
(4) Montori VM, Kleinbart J, Newman TB et al. Tips for learners of evidence-based medicine: 2. Measures of precision (confidence intervals).[erratum appears in CMAJ. 2005 Jan 18;172(2):162]. CMAJ: Canadian Medical Association Journal 171(6):611-5, 2004 September 14.
(5) Barratt A, Wyer PC, Hatala R et al. Tips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat.[see comment]. CMAJ: Canadian Medical Association Journal 171(4):353-8, 2004 August 17.
(6) Wyer PC, Keitz S, Hatala R et al. Tips for learning and teaching evidence-based medicine: introduction to the series.[see comment]. CMAJ: Canadian Medical Association Journal 171(4):347-8, 2004 August 17.
(1) Williams, BC, Hoffman RM. Teaching Tips – A new series in JGIM. Journal of General Internal Medicine 23(1):112-113, 2008 January.
(2) Richardson WS, Wilson MC, Keitz SA, Wyer PC, for the Evidence-Based Medicine Teaching Scripts Working Group. Tips for teachers of evidence-based medicine: making sense of diagnostic test results using likelihood ratios. Journal of General Internal Medicine 23(1):87-92, 2008 January.
(3) Kennedy CC, Jaeschke R, Keitz S, Newman T, Montori V, Wyer PC, Guyatt G, for the Evidence-Based Medicine Teaching Tips Working Group. Tips for teachers of evidence-based medicine: adjusting for prognostic imbalances (confounding variables) in studies on therapy or harm. Journal of General Internal Medicine 23(3):337-43, 2008 March.
(4) Prasad K, Jaeschke R, Wyer P, Keitz S, Guyatt G, for the Evidence-Based Medicine Teaching Tips Working Group. Tips for teachers of evidence-based medicine: understanding odds ratios and their relationship to risk ratios. Journal of General Internal Medicine 23(5):635-40, 2008 May.
(5) McGinn T, Jervis R, Wisnivesky J, Keitz S, Wyer PC, for the Evidence-Based Medicine Teaching Tips Working Group. Tips for teachers of evidence-based medicine: clinical prediction rules (CPRs) and estimating pretest probability. Journal of General Internal Medicine 23(8):1261-8, 2008 August.
This page contains a variety of excellent EBM tutorials and links to additional sites of interest.
Evidence Based Medicine Tool Kit
Centre for Evidence-Based Medicine, University Health Network, University of Toronto
Oxford Centre for Evidence Based Medicine
Introduction to Evidence Based Medicine
Navigating the Maze: Obtaining Evidence-Based Medical Information
Health Links, Evidence-Based Practice, University of Washington
The Canadian Cochrane Network and Centre